Enhancing the Cell Permeability of Stapled Peptides with a Cyclic Cell-Penetrating Peptide
نویسندگان
چکیده
منابع مشابه
Identification and characterization of a new family of cell-penetrating peptides: cyclic cell-penetrating peptides.
Cell-penetrating peptides can translocate across the plasma membrane of living cells and thus are potentially useful agents in drug delivery applications. Disulfide-rich cyclic peptides also have promise in drug design because of their exceptional stability, but to date only one cyclic peptide has been reported to penetrate cells, the Momordica cochinchinensis trypsin inhibitor II (MCoTI-II). M...
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ژورنال
عنوان ژورنال: Journal of Medicinal Chemistry
سال: 2019
ISSN: 0022-2623,1520-4804
DOI: 10.1021/acs.jmedchem.9b00456